Abnormal tissue expression of the tumor-suppressor gene _____ is seen in the pterygium tissue
#2
What is the mechanism that results in malignancy from the c-MYC oncogene?_____
#3
What is the first cancer to be directly associated with genetic abnormality?_____
#4
HER2-_____ cancers are most common subtype of breast cancer in patients with germline mutations in TP53 (Li Fraumeni syndrome)
#5
_____ is a molecular test in breast cancer that is a 21-gene assay
#6
What is the mechanism that results in malignancy from the cyclin D1 oncogene?_____
#7
_____ syndrome is most commonly characterized by a 47,XXY karyotype
#8
_____ disease is due to a deletion of the VHL gene on chromosome 3p, leading unregulated activity of HIF1a
#9
Mutations that cause _____ of the HER2 receptor can precipitate development of certain Breast* and Gastric* Cancers by amplifying the signal transduction
#10
Over 85% of mutations in the FGFR3 gene occur _____ and are related to increased paternal age
Molecular Oncology Indian Medical PG Flashcards - Medical Study Cards
Master Molecular Oncology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Molecular Oncology Flashcard Deck - 10 Cards
Flashcard 1: Abnormal tissue expression of the tumor-suppressor gene _____ is seen in the pterygium tissue
Answer: p53
Flashcard 2: What is the mechanism that results in malignancy from the c-MYC oncogene?_____
Answer: t(8
Flashcard 3: What is the first cancer to be directly associated with genetic abnormality?_____
Answer: Retinoblastoma
Flashcard 4: HER2-_____ cancers are most common subtype of breast cancer in patients with germline mutations in TP53 (Li Fraumeni syndrome)
Answer: positive
Flashcard 5: _____ is a molecular test in breast cancer that is a 21-gene assay
Answer: Oncotype Dx
Flashcard 6: What is the mechanism that results in malignancy from the cyclin D1 oncogene?_____
Answer: t(11
Flashcard 7: _____ syndrome is most commonly characterized by a 47,XXY karyotype
Answer: Klinefelter
Flashcard 8: _____ disease is due to a deletion of the VHL gene on chromosome 3p, leading unregulated activity of HIF1a
Answer: Von Hippel-Lindau
Flashcard 9: Mutations that cause _____ of the HER2 receptor can precipitate development of certain Breast* and Gastric* Cancers by amplifying the signal transduction
Answer: overexpression
Flashcard 10: Over 85% of mutations in the FGFR3 gene occur _____ and are related to increased paternal age
Answer: sporadically
Keywords: Molecular Oncology flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
Want unlimited flashcards?
Get full access to all flashcards, spaced repetition, and progress tracking.
