Cytogenetics — Flashcards

_____ is a process in which metaphase chromosomes are stained, ordered, and numbered according to morphology, size, arm-length ratio, and banding pattern

In _____, 23 distinct fluorescent colours are made by mixing 5 fluorophores and each chromosome is identified by a unique colour.

A ring chromosome is denoted by the symbol _____ in human genetics.

_____ is chromosomal rearrangement between non-homologous chromosomes

The banding technique used for dicentric chromosomes is _____ banding.

Robertsonian translocation leading to Down's syndrome will involve the fusion of long arms of chromosomes _____ and 21

Translocation in Philadelphia chromosome is best studied by using _____

_____ disease is due to a deletion of the VHL gene on chromosome 3p, leading unregulated activity of HIF1a

Mutations that cause _____ of the HER2 receptor can precipitate development of certain Breast* and Gastric* Cancers by amplifying the signal transduction

_____ syndrome is most commonly characterized by a 47,XXY karyotype