HIV and Retroviruses — Flashcards

Ebola virus is highly virulent and requires maximum containment facilities (Biosafety Level _____) for laboratory work.

Quantitative infectivity assay of viruses is done by _____

_____ of HIV binds CD4, and the co-receptors CXCR4 (primarily on T cells), and CCR5 (primarily on macrophages).

The _____ gene of HIV encodes the enzymes reverse transcriptase, aspartate protease, and integrase

In _____ HIV infection, HIV gains entry into Helper T-cells via binding to CD4 plus the coreceptor CXCR4

Hint: early or late

HIV infects _____, macrophages, and dendritic cells

During the window period HIV infection can be detected using _____

HIV reverse transcriptase is a _____-dependent DNA polymerase that synthesizes dsDNA from ssRNA

Once HIV is inside a cell, viral _____ converts viral RNA to double-stranded DNA (dsDNA).This double-stranded DNA is inserted into the host cell genome by integrase, another viral enzyme.

Which virus is displayed below? _____