Major Histocompatibility Complex — Flashcards

Major Histocompatibility Complex — Flashcards

Major Histocompatibility Complex — Flashcards
#1

MHC _____ presents endogenously synthesized antigens to CD8+ cytotoxic T cells

#2

_____ Lymphoid Cell Function B & T cells - Found in bloodstream, lymph nodes, spleen, submucosa, and epithelia B cells: contain markers CD19, CD20, CD21 - Mature into plasma cells - Function is to produce antibodies TH cells: contain markers CD3 and CD4 - Function is to regulate immune responses Cytotoxic T cells: contain markers CD3 and CD8 - Function is to kill infected cells NK cells - Contain markers CD16 and CD56 - Function is to kill tumor/virus cell targets or antibody-coated target cells - T cells can only bind peptides that have been processed and presented by major histocompatibility complexes (MHCs)

#3

CD79a and CD79b are present on _____ cells essential for signal transduction through the antigen receptor.

#4

MHC _____ presents exogenously synthesized antigens to CD4+ helper T cells

#5

The antigen receptors of T lymphocytes have one _____ and beta chain (monovalent)

#6

father of immunology is

#7

_____ cells are induced to kill cells that have an absence of MHC I on their cell surface

#8

Type I interferons (IFN-/IFN-B) work by _____ cells to the products of viral replication

#9

The enzymes responsible for gene recombination in heavy and light chains are encoded by the genes _____ and RAG2

#10

IFN-Y is primarily produced by _____ cells and primarily activates Macrophages and NK cells, along with CD8 CTLs

Want unlimited flashcards?

Get full access to all flashcards, spaced repetition, and progress tracking.

Start For Free