Second Messengers in Signal Transduction — Flashcards

Protein kinase G activates the enzyme _____, which dephosphorylates myosin light chain causing smooth muscle relaxation

In the adenylyl cyclase mechanism of cellular signaling, the second messenger _____ activates protein kinase A, which then phosphorylates specific proteins to produce physiologic actions

Gi proteins _____ the cAMP signaling cascade

In the phospholipase C mechanism of cellular signaling, the _____ generated from PIP2 causes release of Ca2+ from intracellular stores in the endoplasmic or sarcoplasmic reticulum

Once nitric oxide diffuses into muscle cells, it activates soluble (cytosolic) guanylyl cyclase, which converts _____ to cGMP

Binding of atrial natriuretic peptide to its receptor guanylyl cyclase causes conversion of _____ to cGMP

Gq proteins _____ the IP3-DAG signaling cascade

The events that occur during the activation of GPCR are as follows: No answer _____

Cyclin _____ and Cyclin E-CDK2 drive cells from G1 to S phase

Cyclin _____ and Cyclin A-CDK1 are active in S phase