Insulin Signaling Pathway — Flashcards

Insulin Signaling Pathway — Flashcards

Insulin Signaling Pathway — Flashcards
#1

_____ of the insulin receptor allows binding of insulin receptor substrate 1 (IRS-1)

#2

NF-kB activation pathway: IkB kinase phosphorylates the _____ complex, leading to ubiquitination of IkB

#3

The most important of the somatomedins is _____, also known as IGF-1

#4

In the first step of the adenylyl cyclase and phospholipase C mechanism of signaling, binding of hormone to its receptor causes release of _____ from its subunit (s, i, or aq) and replacement by GTP

#5

PTCH1 is a membrane receptor and a _____ regulator of the Hedgehog signaling pathway.

Hint: positive/negative

#6

Glycogen phosphorylase is regulated by positive feedback by _____ via the alpha receptor (liver and muscle)

#7

The events that occur during the activation of GPCR are as follows: No answer _____

Flashcard 7 image
#8

Cyclin _____ and Cyclin A-CDK1 are active in S phase

#9

Cyclin _____ and Cyclin E-CDK2 drive cells from G1 to S phase

#10

_____ is the only known member of the CX3C chemokine group.

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Insulin Signaling Pathway Flashcards | Signal Transduction Study Cards - OnCourse