Nucleotide Degradation and Salvage Pathways — Flashcards

Which enzyme is an alternative pathway for conversion of Adenine to AMP via the salvage pathway?_____

Inosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

The enzyme _____ is an important enzyme for de novo purine production, which converts PRPP to an intermediate used in the generation of IMP

Guanosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

Besides inhibiting Thymidine production, THF is also involved in the formation of _____, as well as some amino acids

Xanthine may be converted to _____ via the enzyme xanthine oxidase

Orotic acid is combined with _____ to form UMP (pyrimidine synthesis)

Pyrimidine synthesis begins with _____, CO2, and 2 ATP

Which base excision repair enzymes are responsible for filling and sealing the gap from the excised bases?_____ (filling) and DNA ligase III (sealing)

Hint: specific