Mutations and DNA Repair — Flashcards

Mutations and DNA Repair — Flashcards

Mutations and DNA Repair — Flashcards
#1

Mitochondrial DNA has a _____ mutation rate than that of nuclear DNA

#2

_____ radiation results in the formation of double-stranded breaks in DNA and hydroxyl free radicals which damage DNA

#3

DNA repair is carried out by DNA polymerase _____.

#4

What is the direction of DNA repair?_____

#5

Which base excision repair enzymes are responsible for filling and sealing the gap from the excised bases?_____ (filling) and DNA ligase III (sealing)

Hint: specific

#6

The _____ is the site where RNA polymerase II and general transcription factors bind to DNA upstream from a gene locus

#7

Guanosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

#8

Hypoxanthine is converted to _____ via xanthine oxidase

#9

microRNA often leads to the _____ of target mRNA, thus causing decreased translation into protein

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Mutations and DNA Repair Flashcards | Nucleic Acid Biochemistry Study Cards - OnCourse