DNA Replication and Repair Mechanisms — Flashcards

In Nonhomologous End Joining (NHEJ), dsDNA breaks are recognized by _____, recruiting the MRN complex which then recruits the Artemis protein and various others to help repair the damage

In Homologous Recombination, dsDNA breaks are recognized by the _____ protein and the FA Core Complex, which activate BRCA1/2 to recruit enzymes to repair the break

_____ is the branch of molecular biology that deals with the study of heritable changes in gene function not involving changes in the DNA sequence.

A _____ is bacteria with plasmids containing DNA fragments representing the majority of the genetic information from a plant or animal.

First step of initiation of mRNA synthesis involves _____ of the ribosome

Phosphorylation of histone _____ is associated with the condensation of chromosomes during the replication cycle.

_____ assay is used in the screening of recombinant vectors for inserted DNA fragments

_____ refers to a rearrangement that involves two breaks within a single chromosome with reincorporation of the inverted, intervening segment.

FISH may be carried out in Metaphase or _____phase of the cell cycle.

_____ test is a widely used biological assay to assess the mutagenic potential of chemical compounds.