Interorgan Metabolite Exchange — Flashcards

Interorgan Metabolite Exchange — Flashcards

Interorgan Metabolite Exchange — Flashcards
#1

Glucagon acts on the _____ (primarily) and adipose tissue

#2

After three days of starvation, the main source of energy for the brain becomes _____ from adipose stores

#3

Urea cycle and Krebs cycle are linked at _____

#4

Increased glucagon (fasting) leads to increased cAMP and protein kinase A, thus _____ activity of FBPase-2 and decreasing activity of PFK-2

#5

In starvation, the enzyme 5'-deiodinase is _____ in tissues such as skeletal muscle, but not inhibited in the other tissues, such as the brain

#6

In a person starving for more than 18 hours, the source of energy is _____.

#7

Effect of diabetes on hepatic glycolysis: no answer _____ - No PFK-2 due to lack of insulin - No glucose trapping in liver leads to elevated blood glucose (hyperglycemia)

Flashcard 7 image
#8

Glucagon causes _____ fatty acid synthesis and increased lipolysis, which shunts substrates towards gluconeogenesis

#9

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of _____ -> malate, thus preventing gluconeogenesis

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