Lipid Metabolism — Flashcards

In the cytosol, _____ may be converted to acetyl-CoA via the enzyme ATP citrate lyase (fatty acid synthesis)

_____ deficiency may cause dicarboxylic acidemia/aciduria due to omega oxidation of fatty acids

Increased levels of cholesterol inside the hepatocyte leads to _____ activity of the enzyme ACAT

_____ is a protease produced by the liver that leads to degradation of hepatocyte LDL receptors

HMG CoA reductase is regulated via negative feedback by _____ and cholesterol

In the blood, chylomicrons pick up apoprotein _____ and E from circulating HDL

Further removal of triglycerides from IDL, via the enzyme _____, leads to the formation of LDL

In the ovaries, _____ cells synthesize pregnenolone from cholesterol via the enzyme cholesterol desmolase

HMG CoA is converted to _____ via the enzyme HMG CoA reductase (cholesterol synthesis)

HMG CoA reductase is regulated via positive feedback by _____ and thyroxine (T4)