Lipid Metabolism — Flashcards

_____-carbon steroids, such as DHEA and androstenedione, have androgenic activity and are precursors to estrogen

_____ causes atherosclerosis whereas apolipoprotein-A prevents atherosclerosis

In extrahepatic tissues, acetoacetate is activated to _____ via the enzyme thiophorase (ketone body metabolism)

Type _____ familial dyslipidemia is due to either:- absent or defective LDL receptors - defective Apo B-100

Type _____ lipoproteinemia is due to a LPL or apo-CII deficiency

In the _____ cells of the ovary, androstenedione is converted to testosterone via the enzyme 17-hydroxysteroid dehydrogenase

Fatty acid synthesis predominantly occurs in the _____, lactating mammary glands (women), and adipose tissue

Fatty acid synthesis requires _____, which is provided directly from citrate

Malonyl-CoA may be converted to _____ via the enzyme fatty acid synthase

Cholesterol synthesis:Condensation of six _____ units form squalene