Lipid Metabolism — Flashcards

Acetyl-CoA is converted to _____ via the enzyme acetyl-CoA carboxylase (fatty acid synthesis)

The serum lipoproteins elevated in type III familial dyslipidemia are _____ and VLDL

Cholesterol synthesis:Condensation of six _____ units form squalene

Fatty acid synthesis requires _____, which is provided directly from citrate

Type _____ lipoproteinemia is due to a LPL or apo-CII deficiency

Peroxisomal beta-oxidation of VLCFAs lead to the formation of _____ and H2O2

Type _____ familial dyslipidemia is due to either:- absent or defective LDL receptors - defective Apo B-100

Malonyl-CoA may be converted to _____ via the enzyme fatty acid synthase

Fatty acid synthesis predominantly occurs in the _____, lactating mammary glands (women), and adipose tissue

In extrahepatic tissues, acetoacetate is activated to _____ via the enzyme thiophorase (ketone body metabolism)