Hemoglobin Synthesis — Flashcards

#1

_____ is due to deficiency of the enzyme uroporphyrinogen decarboxylase

#2

Lead (Pb) poisoning leads to inhibition of the enzymes _____ and ferrochelatase (heme synthesis)

#3

Hb _____ results from globin chain mutations that stabilize iron in the ferric state, leading to congenital methemoglobinemia.

#4

_____, probably acting through an aporepressor molecule, acts as a negative regulator of the synthesis of ALA Synthase-1 in the hepatic biosynthesis of Heme

#5

Chromosome 11, apart form the -globin chain also synthesizes the _____ chain of embryonic Hb

#6

Which enzyme is defective in X-linked porphyria?_____

#7

Uroporphyrinogen III is converted to _____ via the enzyme uroporphyrinogen decarboxylase (heme synthesis)

#8

-aminolevulinic acid is converted to _____ via the enzyme -aminolevulinic acid dehydratase (heme synthesis)

#9

Each subunit of hemoglobin contains a _____ moiety, which is an iron-binding porphyrin, and a polypeptide chain

#10

_____ is the most commonly used indicator for iron in low anemic areas

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Hemoglobin Synthesis Flashcards | Hemoglobin and Iron Metabolism Study Cards - OnCourse