Mitochondrial Diseases — Flashcards

#1

NADH electrons from glycolysis enter the mitochondria via the _____ or glycerol-3-phosphate shuttle

#2

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of _____ -> lactate, thus increasing risk for lactic acidosis

#3

Neuropathy Ataxia Retinitis Pigmentosa syndrome is described as a _____ function disorder.

#4

Propionyl-CoA is converted to _____ via the enzyme propionyl-CoA carboxylase

#5

Creatine phosphate occurs in vertebrate skeletal muscle, _____, spermatozoa, and brain.

#6

_____ is combined with oxaloacetate via the enzyme citrate synthase, forming citrate

#7

Isocitrate is converted to _____ via the enzyme isocitrate dehydrogenase

#8

_____ is an inhibitor of complex III of the ETC

#9

Thyroid Peroxidase is involved in the second part of T4 synthesis, generating _____ and T4 bound to thyroglobulin

#10

O2 is converted to _____ by the enzyme NADPH oxidase (oxidative burst)

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Mitochondrial Diseases Flashcards | Energy Production and Metabolism Study Cards - OnCourse