Drug Metabolism — Flashcards

#1

In the liver, unconjugated bilirubin is converted to _____ via the enzyme UDP-glucuronyl transferase

#2

Which is the rate-limiting step for the entire process of hepatic bilirubin metabolism?_____

#3

Anti-oxidants can be classified as _____ or preventive

#4

In liver, the _____ pathway is the source of glucuronic acid for conjugation of many endogenous and exogenous substances.

#5

_____ conjugation is the only phase II metabolic reaction that is carried out by microsomal enzymes

#6

In the _____, ethanol may be converted to acetaldehyde via the enzyme catalase

#7

In liver _____, ethanol may be converted to acetaldehyde via the enzyme CYP2E1

#8

Carcinoid tumors often secrete _____, which is dumped into the portal vein and processed by the liver via monoamine oxidase (MAO)

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Drug Metabolism Flashcards | Detoxification Pathways Study Cards - OnCourse