Biotransformation in Liver Disease — Flashcards

Biotransformation in Liver Disease — Flashcards

Biotransformation in Liver Disease — Flashcards
#1

Which is the rate-limiting step for the entire process of hepatic bilirubin metabolism?_____

#2

Cytochrome p450 is a _____-oxygenase

#3

In liver _____, ethanol may be converted to acetaldehyde via the enzyme CYP2E1

#4

In the _____, ethanol may be converted to acetaldehyde via the enzyme catalase

#5

Anti-oxidants can be classified as _____ or preventive

#6

Carcinoid tumors often secrete _____, which is dumped into the portal vein and processed by the liver via monoamine oxidase (MAO)

#7

In liver, the _____ pathway is the source of glucuronic acid for conjugation of many endogenous and exogenous substances.

#8

_____, a by-product of G6PD, is needed to regenerate reduced glutathione

#9

Ethanol has many methods of carcinogenic activity including:(1) - metabolites forming DNA _____(2) - depletion of S-adenosylmethionine (SAM)(3) - stimulating the Epithelial-Mesenchymal Transition

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Biotransformation in Liver Disease Flashcards | Detoxification Pathways Study Cards - OnCourse