Chemistry and Mechanism of Action — Flashcards

Highest blood concentrations of local anesthetic are seen after IV injection f/b _____ injection

Commercially available local anaesthetic solutions have an acidic pH in order to maximize the stability, hence should be _____ before use

_____ acting local anesthetics are preferred for prolonged pain relief, such as in brachial plexus block

Ropivacaine has a _____ duration of action than bupivacaine

Bupivacaine has a tendency to provide more _____ block over motor block (sensory/motor)

Administration of 20% _____ therapy is considered at first signs of local anaesthesia systemic toxicity (LAST), after airway management

Alkalinization of local anesthetics can lead to a _____ onset of action and improved quality of block

Neurotoxicity from neuro-axial (epidural or spinal) placement of local anesthetic solution is maximum with _____

_____ is the mainstay rx for cardiac arrest due to bupivacaine