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Rhinitis - Classy Congestion

  • Nasal mucosa inflammation: sneezing, rhinorrhea, blockage, itching.
  • Types: 📌 Allergic, Infective, Non-allergic, Other (AINO).
    • Allergic: IgE-mediated. Intermittent (seasonal) / Persistent (perennial). Pale, boggy turbinates.
    • Infective: Viral (common cold), bacterial (secondary), fungal.
    • Non-Allergic:
      • Vasomotor: environmental triggers.
      • NARES: eosinophilic.
      • Drug-induced: e.g., aspirin, topical decongestants (medicamentosa).
      • Gustatory: food triggers.
    • Other: Atrophic (Ozena), Hormonal (pregnancy). Turbinate Hypertrophy: Normal vs. Enlarged

⭐ Rhinitis Medicamentosa: Rebound nasal congestion due to prolonged (>5-7 days) use of topical vasoconstrictors (e.g., oxymetazoline).

Rhinitis - Pollen Panic

  • Type I IgE-mediated hypersensitivity reaction to aeroallergens (e.g., pollen, dust mites).
  • Pathophysiology: IgE-mediated. Initial allergen exposure (sensitization) → IgE production → IgE binds mast cells. Re-exposure → allergen binds IgE on mast cells → degranulation.
  • Clinical Features:
    • Paroxysmal sneezing, watery rhinorrhea, nasal obstruction, itching (nose, palate, eyes).
    • Allergic salute, allergic shiners (infraorbital dark circles), Dennie-Morgan lines (infraorbital folds). 📌 "SAD" for Signs: Shiners, Allergic Salute, Dennie's lines.
  • Diagnosis: Clinical history, Skin Prick Test (SPT), Serum specific IgE. Nasal eosinophilia.
  • Management:
    • Allergen avoidance.
    • Pharmacotherapy: Intranasal corticosteroids (INCS), antihistamines (oral/intranasal), decongestants, Leukotriene Receptor Antagonists (LTRAs).
    • Immunotherapy (allergy shots/sublingual).

⭐ Intranasal corticosteroids are the most effective single medication for controlling symptoms of persistent allergic rhinitis. image

Rhinitis - Phantom Drips

  • Post-nasal drip (PND) sensation, often without objective copious discharge or with an unclear cause.
  • Key Differentials & Management:
    • Laryngopharyngeal Reflux (LPR):
      • Gastric reflux irritating larynx/pharynx.
      • Symptoms: Globus, throat clearing, chronic cough, hoarseness.
      • Dx: Clinical, laryngoscopy. Rx: Proton Pump Inhibitors (PPIs), lifestyle changes.
    • Vasomotor Rhinitis (Idiopathic Non-Allergic):
      • Intermittent nasal congestion, watery rhinorrhea, PND.
      • Triggers: Temperature/humidity changes, strong odors, stress.
      • Rx: Intranasal corticosteroids (INCS), intranasal azelastine, ipratropium.
    • Gustatory Rhinitis:
      • Watery rhinorrhea after ingesting specific (e.g., spicy, hot) foods.
      • Rx: Ipratropium nasal spray before meals.
  • Evaluation: Detailed history, nasal endoscopy. Rule out allergic rhinitis, sinusitis.

⭐ Laryngopharyngeal Reflux (LPR) is a key cause of "phantom drip" sensation; laryngeal symptoms often predominate over nasal symptoms in such cases.

Rhinitis - Germ Warfare

  • Viral Rhinitis (Common Cold): Most common; Rhinovirus, Coronavirus. Self-limiting.
  • Bacterial Rhinitis: Often secondary to viral infection. Streptococcus pneumoniae, Haemophilus influenzae.
  • Fungal Rhinitis: Invasive (immunocompromised) vs. non-invasive (fungal ball, allergic fungal rhinosinusitis - AFRS).
    • AFRS: Type I & III hypersensitivity. Charcot-Leyden crystals.
  • Atrophic Rhinitis (Ozena): Chronic, progressive nasal atrophy. Greenish crusts (foetid odor). Klebsiella ozaenae implicated. Young females. 📌 Mnemonic: "Empty Nose, Smelly Nose".
  • Rhinoscleroma: Chronic granulomatous; Klebsiella rhinoscleromatis. Mikulicz cells, Russell bodies. Stages: Catarrhal → Atrophic/Granulomatous → Sclerotic.

Mikulicz cells in rhinoscleroma

High-Yield Fact: In Rhinoscleroma, the "Hebra nose" (broad, flattened nose) can be a characteristic late finding due to tissue infiltration and fibrosis of the external nose and upper lip (Woody induration).

Rhinitis - Nose Alerts

  • Warning Signs:
    • Unilateral nasal obstruction, discharge, pain, or epistaxis
    • Facial swelling, erythema, or severe tenderness
    • Orbital signs: proptosis, diplopia, impaired vision
    • Neurological: severe headache, fever, altered sensorium
    • Cacosmia
    • Persistent symptoms despite treatment

⭐ Unilateral bloody nasal discharge in an adult is a red flag for nasopharyngeal carcinoma or inverted papilloma.

High‑Yield Points - ⚡ Biggest Takeaways

  • Allergic rhinitis is IgE-mediated with nasal eosinophilia and pale, boggy turbinates.
  • NARES (Non-Allergic Rhinitis with Eosinophilia Syndrome) presents with nasal eosinophilia but negative allergy tests.
  • Rhinitis medicamentosa results from rebound congestion due to prolonged topical decongestant use (e.g., oxymetazoline).
  • Atrophic rhinitis (Ozena) features nasal crusting, fetor, wide nasal cavities, and is associated with Klebsiella ozaenae.
  • Vasomotor rhinitis is non-allergic, non-infectious, triggered by environmental factors like temperature or humidity changes.
  • Samter's Triad is the association of nasal polyps with asthma and aspirin sensitivity.
  • Allergic Fungal Rhinosinusitis (AFRS) is characterized by allergic mucin containing fungal hyphae without tissue invasion.

Practice Questions: Rhinitis

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A patient presents with headache for one hour on awakening, associated with nasal stuffiness and reddening of eye. Suggestive of

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Flashcards: Rhinitis

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_____ is also known as nasal cholesteatoma.

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_____ is also known as nasal cholesteatoma.

Rhinitis caseosa

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