Dialysis access procedures and complications

Dialysis access procedures and complications

Dialysis access procedures and complications

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🩸 Anatomy - Plumbing for Purity

  • Access Types & Preference:

    • Arteriovenous Fistula (AVF): Direct artery-to-vein anastomosis. Best patency, lowest infection rate.
    • Arteriovenous Graft (AVG): Synthetic tube connecting artery and vein.
    • Central Venous Catheter (CVC): Tunneled catheter (e.g., Permacath). Highest infection risk; used for immediate/temporary access.
  • Common AVF Sites (Distal to Proximal):

    • Radiocephalic (Brescia-Cimino): Radial artery & cephalic vein.
    • Brachiocephalic: Brachial artery & cephalic vein.

Rule of 6s for AVF Maturation: A usable fistula should be:

  • Flow > 600 mL/min
  • Diameter > 6 mm
  • Depth < 6 mm from skin
  • Matures in ~6 weeks

📌 Mnemonic: "Fistula First" - the preferred primary access.

Dialysis Graft Flow Dynamics and Anastomosis

💉 Clinical - The Access Trinity

📌 Fistula > Graft > Catheter. Choice depends on urgency and vessel quality.

  • AV Fistula (AVF): Gold standard; direct artery-vein connection (e.g., radiocephalic).
    • Pros: Best long-term patency, lowest infection/thrombosis risk.
    • Cons: Requires ~2-3 months to mature; potential for steal syndrome.
  • AV Graft (AVG): Synthetic (PTFE) tube connects artery to vein.
    • Pros: Usable sooner (2-4 weeks); for patients with inadequate veins.
    • Cons: Higher thrombosis, stenosis, and infection risk than AVF.
  • CVC: Tunneled catheter for temporary/bridge access.
    • Pros: Immediate use.
    • Cons: ⚠️ Highest infection risk (S. aureus bacteremia), central venous stenosis.

⭐ The most common cause of AVF/AVG failure is thrombosis, typically due to stenosis at the venous anastomosis. Loss of a palpable thrill or audible bruit is a key sign.

💔 Complications - When Lifelines Fail

  • Thrombosis: Most common cause of access failure.
    • Sx: Sudden loss of thrill/bruit.
    • Tx: Pharmacomechanical thrombectomy or surgical thrombectomy.
  • Stenosis: Typically at the venous anastomosis.
    • Sx: ↑ venous pressures during dialysis, prolonged bleeding post-cannulation, limb swelling.
    • Dx: Duplex US; fistulogram is gold standard.
    • Tx: Balloon angioplasty ± stenting.
  • Infection: Risk: Catheter > Graft (AVG) > Fistula (AVF).
    • Pathogen: S. aureus is most common.
    • Tx: IV antibiotics; may require graft excision for AVG infection.
  • Dialysis Access Steal Syndrome (DASS):
    • Patho: Ischemia distal to access due to shunting of arterial blood.
    • Sx: Pain (especially with exertion/dialysis), pallor, paresthesias, cool digits.
  • Aneurysm/Pseudoaneurysm:
    • Cause: High flow, repeated needle sticks weaken the wall.
    • Tx: Surgical repair if symptomatic, rapidly expanding, or skin erosion.

⭐ New-onset hand pain, numbness, and coolness after AV fistula creation is classic for Dialysis Access Steal Syndrome (DASS).

Dialysis Access Steal Syndrome Ligation Diagram

🔧 Management - Salvage Operations

  • Goal: Preserve existing access & avoid new access creation.
  • Primary Interventions: Endovascular approaches are first-line.
    • Thrombectomy: For clotted access. Can be percutaneous (pharmacomechanical) or open surgical.
    • Angioplasty (PTA): Balloon dilation for stenosis. Stents used for elastic recoil or recurrent lesions.
  • Surgical Revisions:
    • Anastomotic revision/Interposition graft: For complex stenosis or aneurysmal changes.
    • Banding/DRIL: For dialysis-associated steal syndrome to ↓ flow.

⭐ The most common site of stenosis in an AV fistula is the venous outflow tract, just distal to the anastomosis.

⚡ Biggest Takeaways

  • AV fistula (AVF) is the preferred access: best patency, lowest infection/thrombosis rates.
  • AVFs require ~6-8 weeks to mature ("Rule of 6s"); grafts are usable in ~2-3 weeks.
  • Stenosis and thrombosis are the most common complications of AVF/AVG, often at the venous anastomosis.
  • Central venous catheters have the highest risk of infection (S. aureus) and central vein stenosis.
  • Dialysis steal syndrome causes distal limb ischemia (pain, pallor) after access creation.
  • High-output heart failure is a rare complication from excessive shunting through large, proximal access.

Practice Questions: Dialysis access procedures and complications

Test your understanding with these related questions

A 31-year-old woman returns to her primary care provider for a follow-up visit. At a routine health maintenance visit 2 months ago, her blood pressure (BP) was 181/97 mm Hg. She has adhered to a low-salt diet and exercises regularly. On repeat examination 1 month later, her BP was 178/93, and she was prescribed hydrochlorothiazide and lisinopril. The patient denies any complaint, except for occasional headaches. Now, her BP is 179/95 in the right arm and 181/93 in the left arm. Physical examination reveals an abdominal bruit that lateralizes to the left. A magnetic resonance angiogram of the renal arteries is shown in the image. Which of the following is the best next step for the management of this patient condition?

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Flashcards: Dialysis access procedures and complications

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EF < _____% and MI within _____ months are absolute contraindications to non-cardiac surgery

TAP TO REVEAL ANSWER

EF < _____% and MI within _____ months are absolute contraindications to non-cardiac surgery

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