Ileus and bowel dysfunction

Ileus and bowel dysfunction

Ileus and bowel dysfunction

On this page

Ileus & SBO - The Great Gut Slowdown

  • Ileus: Functional, non-mechanical obstruction. Uniformly dilated bowel loops. Common causes: post-op state, opioids, hypokalemia, sepsis.
  • Small Bowel Obstruction (SBO): True mechanical blockage. Key finding: transition point with dilated proximal bowel and collapsed distal bowel. Common causes: Adhesions (>75%), hernias, tumors.

image

⭐ The most common cause of SBO is post-surgical adhesions. In a "virgin" abdomen (no prior surgery), incarcerated hernias are a primary suspect.

Pathophysiology - Guts on Strike

Post-surgical gut paralysis (ileus) results from a coordinated inflammatory and neurogenic response.

  • Neurogenic Phase (Immediate):
    • Surgical stress activates splanchnic nerves, leading to a surge in sympathetic tone (norepinephrine).
    • Inhibits parasympathetic (vagal) activity, silencing pro-kinetic pathways.
  • Inflammatory Phase (Delayed):
    • Gut handling triggers resident macrophage activation in the muscularis externa.
    • Release of inflammatory mediators (e.g., IL-1α, IL-6, TNF-α) recruits more leukocytes.
    • This inflammatory soup suppresses smooth muscle contractility.

Abdominal X-ray: Dilated bowel loops in paralytic ileus

⭐ Ileus is physiologic for 2-3 days post-op. If it persists beyond 3-5 days (prolonged ileus), it must be distinguished from mechanical obstruction, often requiring CT imaging.

Diagnosis & Workup - Deciphering the Silence

  • Clinical Evaluation:

    • History: Recent surgery, medications (opioids), electrolyte imbalance.
    • Physical Exam: Abdominal distension, minimal tenderness, absent/hypoactive bowel sounds.
  • Imaging Studies:

    • Abdominal X-ray (AXR): First-line test. Shows generalized, uniform dilation of both small and large bowel; no transition point.
    • CT Scan: More specific. Confirms ileus, rules out mechanical obstruction, and can identify underlying causes (e.g., abscess).

Abdominal X-ray: Paralytic ileus with bowel dilation

⭐ On imaging, paralytic ileus is distinguished from SBO by gas and dilation throughout both the small and large bowel, whereas SBO typically shows a clear transition point with distal bowel collapse.

Management - Getting Things Moving

  • Conservative First: NPO/clears, IV fluids, correct electrolytes (K⁺, Mg²⁺), early & frequent ambulation.
  • Decompression: Nasogastric (NG) tube if significant vomiting or distention.
  • Remove Obstacles: Minimize opioids (use multimodal analgesia), treat underlying causes.
  • Pharmacologic Aids:
    • Alvimopan: Peripherally-acting µ-opioid antagonist for postoperative ileus after bowel resection.
    • Chewing gum can act as "sham feeding" to stimulate the vagus nerve.

⭐ Alvimopan is for short-term, inpatient use only (max 7 days or 15 doses) due to an increased risk of myocardial infarction with long-term use.

Abdominal X-ray: Postoperative ileus with dilated bowel

High‑Yield Points - ⚡ Biggest Takeaways

  • Postoperative ileus is a functional, non-mechanical bowel obstruction from inflammatory mediators and ↑ sympathetic tone.
  • Presents with absent bowel sounds, nausea, vomiting, and failure to pass flatus or stool.
  • Physiologic ileus typically resolves within 72 hours; a longer duration is considered prolonged ileus.
  • Opioid use is the most significant risk factor; also check for hypokalemia.
  • Management is supportive: NPO, IV fluids, and minimizing opioids.
  • Differentiate from SBO via X-ray: ileus shows diffusely dilated bowel loops, while SBO has a clear transition point.

Practice Questions: Ileus and bowel dysfunction

Test your understanding with these related questions

A 75-year-old male is hospitalized for bloody diarrhea and abdominal pain after meals. Endoscopic work-up and CT scan lead the attending physician to diagnose ischemic colitis at the splenic flexure. Which of the following would most likely predispose this patient to ischemic colitis:

1 of 5

Flashcards: Ileus and bowel dysfunction

1/6

The iliohypogastric nerve is commonly injured due to post abdominal surgery _____

TAP TO REVEAL ANSWER

The iliohypogastric nerve is commonly injured due to post abdominal surgery _____

sutures

browseSpaceflip

Enjoying this lesson?

Get full access to all lessons, practice questions, and more.

Start Your Free Trial