Spinal fusion procedures

Spinal fusion procedures

Spinal fusion procedures

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🦴 Backbone Bonding Basics

  • Goal: Achieve arthrodesis (bony fusion) between vertebrae to eliminate motion, providing stability and pain relief for conditions like spondylolisthesis or severe degenerative disc disease.
  • Key Components:
    • Bone Graft: The biological "glue" for fusion.
      • Autograft: Iliac crest (gold standard); osteoinductive & osteoconductive.
      • Allograft: Cadaveric bone; osteoconductive only.
    • Instrumentation: Pedicle screws, rods, and cages provide immediate mechanical stability while fusion occurs.

Pseudoarthrosis (failed fusion) is a major complication, presenting as persistent or recurrent pain post-operatively.

Transforaminal Lumbar Interbody Fusion (TLIF) procedure

🔩 Clinical Manifestations - When Spines Need Support

  • Spinal Instability: Pathologic motion causing pain or neurologic deficit.
    • Traumatic: Unstable fractures (e.g., Chance, burst fractures).
    • Neoplastic: Vertebral body tumors causing structural compromise.
    • Infectious: Spondylodiscitis (e.g., Pott's disease) leading to collapse.
    • Iatrogenic: Post-extensive laminectomy.
  • Deformity:
    • Progressive or painful scoliosis/kyphosis.
    • Spondylolisthesis (vertebral slip), especially high-grade (>50%).
  • Degenerative Disease (Refractory):
    • Degenerative Disc Disease with severe, disabling axial back pain.
    • Spinal stenosis with associated instability.

⭐ Fusion is indicated for progressive neurologic deficits (myelopathy, radiculopathy) or intractable pain from mechanical instability, not just for pain alone.

🔩 Management - The Fusion Fix-Up

The primary goal is arthrodesis (bony fusion) to stabilize painful or unstable spinal segments, eliminating motion.

Procedural Flow:

Approaches & Materials:

  • Surgical Paths: Anterior (ALIF), Posterior (PLIF/TLIF), Lateral (XLIF).
  • Bone Graft:
    • Autograft (Iliac Crest): Gold standard; osteogenic, -inductive, & -conductive.
    • Allograft: Cadaveric; mainly osteoconductive.
    • Synthetics: e.g., BMPs; avoid donor site morbidity.
  • Hardware: Pedicle screws & rods provide immediate rigid fixation.

Pseudoarthrosis (failed fusion) is a key long-term complication, presenting as persistent axial pain. Smoking is a major modifiable risk factor.

PLIF with pedicle screws and interbody fusion cage

⚠️ Complications - When Fusion Goes Foul

  • Intraoperative:
    • Nerve root injury → new/worsened radiculopathy.
    • Dural tear → CSF leak (postural headaches).
    • Vascular injury (e.g., great vessels in anterior approaches).
  • Postoperative (Early):
    • Surgical Site Infection (SSI): Superficial or deep (discitis/osteomyelitis).
    • Epidural hematoma → progressive neuro deficit (⚠️ surgical emergency).
  • Postoperative (Late):
    • Hardware Failure: Screw malposition, breakage, cage migration.
    • Pseudoarthrosis: Non-union/failed fusion; persistent pain.

Spinal fusion imaging with measurements

Adjacent Segment Disease (ASD): A key long-term risk. Fusing a segment increases biomechanical stress on the mobile levels above and below, leading to accelerated degeneration, new stenosis, or instability requiring further surgery.

☢️ Radiology - Peeking at the Plates

  • X-ray (AP/Lateral/Flexion-Extension): Initial check for alignment, hardware integrity, and instability.
  • CT Scan: 🥇 Gold standard for evaluating bony fusion (arthrodesis). Best modality to visualize pseudarthrosis (failed fusion).
  • MRI: Assesses soft tissues. Indicated for new/worsening neurologic deficits to rule out hematoma, abscess, or persistent nerve compression.

Cervical spinal fusion X-ray with pedicle screws and rods

Pseudarthrosis: A key complication seen as a radiolucent gap at the fusion site on CT, often with motion on dynamic X-rays. It's a major cause of "failed back surgery syndrome."

⚡ Biggest Takeaways

  • Goal: Stabilize the spine via arthrodesis (bony fusion) for instability, spondylolisthesis, or severe degenerative disease.
  • Technique: Combines bone graft to stimulate fusion with instrumentation (screws, rods) for immediate immobilization.
  • Key failure: Pseudarthrosis (failed fusion) is a primary cause of persistent pain, often requiring revision surgery.
  • Long-term risk: Adjacent Segment Disease (ASD)-accelerated degeneration of levels next to the fusion due to altered biomechanics.
  • Post-op warning: Avoid NSAIDs as they inhibit bone healing, increasing non-union risk.

Practice Questions: Spinal fusion procedures

Test your understanding with these related questions

A 14-year-old girl is brought to the physician for a follow-up examination. She has had frequent falls over the past two years. During the past six months, the patient has been unable to walk or stand without assistance and she now uses a wheelchair. Her mother was diagnosed with a vestibular schwannoma at age 52. Her vital signs are within normal limits. Her speech is slow and unclear. Neurological examination shows nystagmus in both eyes. Her gait is wide-based with irregular and uneven steps. Her proprioception and vibration sense are absent. Muscle strength is decreased especially in the lower extremities. Deep tendon reflexes are 1+ bilaterally. The remainder of the examination shows kyphoscoliosis and foot inversion with hammer toes. This patient is most likely to die from which of the following complications?

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Flashcards: Spinal fusion procedures

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Herniated contents may be at risk for _____, which is characterized by ischemia and necrosis

TAP TO REVEAL ANSWER

Herniated contents may be at risk for _____, which is characterized by ischemia and necrosis

strangulation

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