Monitored anesthesia care

On this page

👀 The Vigilant Watch

  • A specific anesthesia service for procedures performed with local/regional anesthesia.
  • Goals: Provide sedation, anxiolysis, and analgesia while maintaining cardiorespiratory function.
  • Patient typically maintains spontaneous ventilation and airway reflexes, responding to stimuli.
  • The anesthesia provider is always prepared to convert to general anesthesia (GA).

⭐ MAC is distinct from moderate sedation because an anesthesia professional is required, prepared to convert to general anesthesia or rescue the airway at any moment.

🎯 Clinical Uses - Who Gets MAC?

MAC is ideal for procedures where deep sedation isn't needed but patient comfort and safety are paramount. It bridges the gap between local/regional anesthesia and general anesthesia (GA).

  • Common Procedures:

    • Endoscopy (e.g., colonoscopy, EGD)
    • Ophthalmology (e.g., cataract surgery)
    • Minor orthopedic or plastic surgery
    • Interventional radiology/cardiology procedures
  • Patient Selection:

    • Cooperative patients undergoing uncomfortable procedures.
    • Patients too frail or with significant comorbidities (e.g., severe COPD, low EF) for GA.
    • Procedures performed under local or regional anesthesia that may require supplemental sedation/analgesia.

⭐ A key distinction: MAC is always administered by an anesthesia professional prepared to convert to general anesthesia if the patient's condition deteriorates.

💊 Drug Class/MOA - The MAC Cocktail

A synergistic combination tailored for sedation, anxiolysis, and analgesia while maintaining spontaneous respiration.

Drug ClassExample(s)MOA & Key Features
BenzodiazepineMidazolamAnxiolysis/Amnesia. ↑ frequency of GABA-A $Cl^-$ channel opening. Reversible with Flumazenil.
OpioidFentanyl, RemifentanilAnalgesia. Potent μ-opioid receptor agonist. Reversible with Naloxone. Risk of chest wall rigidity.
HypnoticPropofol, Ketamine, DexmedetomidineSedation/Hypnosis. Propofol: Potentiates GABA-A; rapid on/off, hypotension. Ketamine: NMDA antagonist; dissociative, preserves respiratory drive. Dexmedetomidine: α2-agonist.

⚙️ Management - The MAC Workflow

  • Goal: Provide sedation, anxiolysis, and analgesia while preserving spontaneous ventilation and airway reflexes.
  • Titration is key: Adjust drug infusions (e.g., propofol) based on patient response and surgical stimulus.
  • Constant vigilance: Anesthesiologist must be prepared to convert to general anesthesia (GA) if needed.

⭐ MAC is not "light" anesthesia. It requires an anesthesia professional prepared to manage complications, including apnea, airway obstruction, and hemodynamic instability, and convert to general anesthesia if necessary.

⚠️ Complications - When Sedation Slips

  • Primary Risk: Unintended progression to general anesthesia.
  • Respiratory Cascade: Oversedation → airway obstruction (tongue prolapse), hypoventilation, apnea → hypoxia ($SpO_2$ < 90%), hypercarbia.
  • Hemodynamic: Hypotension, bradycardia (common with propofol, opioids).
  • Other Risks: Aspiration (loss of protective reflexes), patient awareness/recall (undersedation).

⭐ The most frequent serious complication of MAC is respiratory depression leading to hypoxia, requiring immediate airway intervention.

High-Yield Points - ⚡ Biggest Takeaways

Error generating content for this concept group: Failed to process successful response

Practice Questions: Monitored anesthesia care

Test your understanding with these related questions

A man is brought into the emergency department by police. The patient was found somnolent in the park and did not respond to questioning. The patient's past medical history is unknown, and he is poorly kempt. The patient's personal belongings include prescription medications and illicit substances such as alprazolam, diazepam, marijuana, cocaine, alcohol, acetaminophen, and a baggie containing an unknown powder. His temperature is 97.0°F (36.1°C), blood pressure is 117/58 mmHg, pulse is 80/min, respirations are 9/min, and oxygen saturation is 91% on room air. Physical exam reveals pupils that do not respond to light bilaterally, and a somnolent patient who only withdraws his limbs to pain. Which of the following is the best next step in management?

1 of 5

Flashcards: Monitored anesthesia care

1/6

EF < _____% and MI within _____ months are absolute contraindications to non-cardiac surgery

TAP TO REVEAL ANSWER

EF < _____% and MI within _____ months are absolute contraindications to non-cardiac surgery

35

browseSpaceflip

Enjoying this lesson?

Get full access to all lessons, practice questions, and more.

Start Your Free Trial