Abdominal compartment syndrome

Abdominal compartment syndrome

Abdominal compartment syndrome

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Pathophysiology - Belly Under Pressure

  • Intra-abdominal Pressure (IAP): Baseline pressure in the abdomen (Normal: 5-7 mmHg).
  • Intra-abdominal Hypertension (IAH): Sustained IAP ≥ 12 mmHg.
  • Abdominal Compartment Syndrome (ACS): Sustained IAP > 20 mmHg with new organ dysfunction.
  • Abdominal Perfusion Pressure (APP): Crucial for organ viability. Calculated as $APP = MAP - IAP$. Goal: >60 mmHg.

Pathophysiology of Abdominal Compartment Syndrome

⭐ Systemic effects of increased IAP include decreased cardiac output, impaired ventilation (increased peak airway pressures), and reduced renal blood flow leading to oliguria.

Etiology & Risk Factors - The Pressure Cookers

  • Primary ACS (Intra-abdominal): Conditions increasing pressure from within the abdomen.

    • Severe trauma (e.g., liver hematoma)
    • Acute pancreatitis
    • Large-volume ascites
    • Ileus or bowel obstruction
  • Secondary ACS (Extra-abdominal): Systemic issues causing third-spacing and abdominal wall edema.

    • Massive fluid resuscitation (e.g., sepsis, burns)
    • Systemic inflammation and capillary leak

⭐ Aggressive fluid resuscitation in trauma or sepsis patients is a leading cause of secondary ACS, even without direct abdominal injury.

Diagnosis - Feeling the Squeeze

Clinical suspicion is key, marked by a tense, distended abdomen, oliguria, hypotension, and rising airway pressures. The gold standard for diagnosis is measuring intra-abdominal pressure (IAP) via a bladder catheter.

  • Intra-Abdominal Hypertension (IAH): IAP > 12 mmHg.
  • Abdominal Compartment Syndrome (ACS): IAP > 20 mmHg with new organ dysfunction (e.g., renal, cardiovascular, respiratory).

⭐ Oliguria that is refractory to fluid boluses is a classic early sign of developing ACS and should prompt immediate IAP measurement.

Intra-abdominal pressure measurement via bladder catheter

Management - Release the Pressure!

  • Medical (Non-operative) Management: Aims to reduce intra-abdominal pressure (IAP) without surgery.
    • Improve Compliance: Sedation, analgesia, consider neuromuscular blockade (paralysis).
    • Evacuate Contents: Nasogastric (NG) and rectal tube decompression.
    • Remove Fluid: Diuretics for fluid overload; percutaneous catheter drainage for ascites.

⭐ Decompressive laparotomy is the definitive, life-saving intervention for established ACS and should not be delayed.

Open laparotomy for abdominal compartment syndrome

High-Yield Points - ⚡ Biggest Takeaways

  • Abdominal Compartment Syndrome (ACS) is defined by sustained intra-abdominal pressure (IAP) > 20 mmHg with new organ dysfunction.
  • Most common after massive fluid resuscitation in trauma, pancreatitis, or major abdominal surgery.
  • Presents with a tense, distended abdomen, oliguria, hypotension, and ↑ airway pressures.
  • Intra-bladder pressure measurement is the gold standard for diagnosis.
  • End-organ damage includes renal failure, cardiovascular collapse (↓ preload), and respiratory failure.
  • Definitive management is urgent decompressive laparotomy to open the abdomen.

Practice Questions: Abdominal compartment syndrome

Test your understanding with these related questions

A 67-year-old woman has fallen from the second story level of her home while hanging laundry. She was brought to the emergency department immediately and presented with severe abdominal pain. The patient is anxious, and her hands and feet feel very cold to the touch. There is no evidence of bone fractures, superficial skin wounds, or a foreign body penetration. Her blood pressure is 102/67 mm Hg, respirations are 19/min, pulse is 87/min, and temperature is 36.7°C (98.0°F). Her abdominal exam reveals rigidity and severe tenderness. A Foley catheter and nasogastric tube are inserted. The central venous pressure (CVP) is 5 cm H2O. The medical history is significant for hypertension. Which of the following is best indicated for the evaluation of this patient?

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Flashcards: Abdominal compartment syndrome

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Cholecystitis can cause _____ formation with the GI tract, resulting in air in the biliary tree (pneumobilia)

TAP TO REVEAL ANSWER

Cholecystitis can cause _____ formation with the GI tract, resulting in air in the biliary tree (pneumobilia)

fistula

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