Diagnostic criteria and subtypes

Diagnostic criteria and subtypes

Diagnostic criteria and subtypes

On this page

Diagnostic Criteria - The Reality Glitch

  • DSM-5: Requires ≥2 of the following symptoms for a significant portion of time during a 1-month period. At least one must be (1), (2), or (3).
    • (1) Delusions
    • (2) Hallucinations
    • (3) Disorganized speech (e.g., frequent derailment or incoherence)
    • (4) Grossly disorganized or catatonic behavior
    • (5) Negative symptoms
  • Duration: Continuous signs of the disturbance must persist for at least 6 months. This 6-month period must include at least 1 month of active-phase symptoms.
  • Dysfunction: Level of functioning in one or more major areas (e.g., work, interpersonal relations, or self-care) is markedly below the level achieved prior to onset.
  • Exclusions: Rule out schizoaffective disorder, depressive or bipolar disorder with psychotic features, substance-induced psychosis, and psychosis due to another medical condition.

⭐ Impaired functioning is key! Unlike some other psychotic disorders (e.g., delusional disorder), schizophrenia diagnosis requires a significant decline in social or occupational performance.

Symptom Domains - Positives vs. Negatives

  • Positive Symptoms: Pathological excesses; behaviors added to the person's repertoire. Linked to ↑ dopamine in the mesolimbic pathway.

    • Delusions: Fixed, false beliefs despite contrary evidence.
    • Hallucinations: Sensory experiences without external stimuli (auditory is most common).
    • Disorganized Speech: Loose associations, tangentiality, word salad.
    • Grossly Disorganized or Catatonic Behavior.
  • Negative Symptoms: Pathological deficits; absence of normal behaviors. Linked to ↓ dopamine in the mesocortical pathway.

    • 📌 The 5 A's:
      • Affect (blunted/flat): Diminished emotional expression.
      • Alogia: Poverty of speech.
      • Avolition: Decreased motivation.
      • Anhedonia: Decreased ability to experience pleasure.
      • Asociality: Lack of interest in social interactions.

⭐ Negative symptoms are major contributors to poor functional outcomes and are generally less responsive to antipsychotic medication than positive symptoms.

Schizophrenia Subtypes - Ghosts of Subtypes Past

  • The DSM-5 eliminated the classical schizophrenia subtypes. They are no longer used for diagnosis but may appear in older questions or clinical charts.
  • Emphasis is now on assessing symptom dimensions (e.g., reality distortion, negative symptoms) for a more precise description.
  • Paranoid Type: Preoccupation with one or more delusions (typically persecutory or grandiose) or frequent auditory hallucinations. Cognitive function and affect are relatively preserved.
  • Disorganized Type: Characterized by disorganized speech, disorganized behavior, and flat or inappropriate affect.
  • Catatonic Type: Dominated by at least two catatonic symptoms (e.g., motor immobility, excessive motor activity, extreme negativism, echolalia/echopraxia).
  • Undifferentiated Type: Symptoms meet criterion A for schizophrenia, but the criteria are not met for the Paranoid, Disorganized, or Catatonic Type.
  • Residual Type: Absence of prominent delusions, hallucinations, or disorganized speech/behavior. Continuing evidence of the disturbance is indicated by the presence of negative symptoms.

⭐ The primary reason for removing subtypes was their poor diagnostic stability, low reliability, and limited clinical utility in predicting treatment response or course of illness.

High-Yield Points - ⚡ Biggest Takeaways

  • Diagnosis requires ≥2 symptoms (one must be delusions, hallucinations, or disorganized speech) for a significant portion of 1 month, with continuous signs for ≥6 months.
  • Social or occupational dysfunction is a core diagnostic requirement.
  • Negative symptoms (avolition, flat affect, alogia) are crucial for diagnosis and portend a poorer prognosis.
  • DSM-5 eliminated subtypes; now use specifiers like "with catatonia".
  • Timeline is key: Brief Psychotic Disorder (<1 month), Schizophreniform (1-6 months), Schizophrenia (≥6 months).

Practice Questions: Diagnostic criteria and subtypes

Test your understanding with these related questions

A 29-year-old woman is brought to the physician by her father because of a change in her behavior over the past 8 months. The father says that his daughter has become increasingly withdrawn; she has not answered any phone calls or visited her family and friends. The patient says that she has to stay at home because a foreign intelligence service is monitoring her. She thinks that they are using a magnetic field to read her mind. Mental status exam shows disjointed and perseverative thinking. She is anxious and has a flat affect. Which of the following is the most likely diagnosis?

1 of 5

Flashcards: Diagnostic criteria and subtypes

1/10

Are typical antipsychotics effective at treating the positive or negative symptoms of schizophrenia? _____

TAP TO REVEAL ANSWER

Are typical antipsychotics effective at treating the positive or negative symptoms of schizophrenia? _____

Positive

browseSpaceflip

Enjoying this lesson?

Get full access to all lessons, practice questions, and more.

Start Your Free Trial