Early intervention in ASD

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Core Principles - The Early Bird Advantage

  • Neuroplasticity: Capitalizes on the brain's high malleability in early childhood (ideally < 3 years old) to rewire neural circuits and improve developmental trajectory.
  • Core Deficit Targeting: Focuses on improving social communication, joint attention, and play skills while reducing restrictive/repetitive behaviors.
  • Key Modalities:
    • Applied Behavior Analysis (ABA): Uses reinforcement to teach new skills.
    • Developmental Models (e.g., ESDM): Relationship-based, integrated into natural routines.
  • Intensity & Duration: Evidence supports intensive intervention, often ≥25 hours/week.
  • Parent/Caregiver Training: Essential for skill generalization.

⭐ Early intensive behavioral intervention (EIBI) can lead to significant gains in IQ, language, and adaptive behavior, with some children achieving functioning within the normal range.

Human Brain Development: Neural Connections by Function

Screening & Diagnosis - Finding the Flags

  • Universal Screening: All children screened at 18 and 24 months.
    • Tool: M-CHAT-R/F (Modified Checklist for Autism in Toddlers, Revised with Follow-up).
  • Comprehensive Evaluation: Triggered by positive screen or clinical concern.
    • Gold Standard Tools:
      • ADOS-2: Autism Diagnostic Observation Schedule (direct child assessment).
      • ADI-R: Autism Diagnostic Interview-Revised (structured parent interview).

Regression of milestones (e.g., loss of language or social skills) at any age is a critical red flag warranting immediate, comprehensive evaluation for ASD.

Intervention Models - The Therapy Toolkit

  • Applied Behavior Analysis (ABA): The most established model. Uses reinforcement principles to ↑ desired behaviors & ↓ challenging ones.

    • Discrete Trial Training (DTT): Structured, one-on-one instruction.
    • Pivotal Response Training (PRT): More naturalistic, targets core developmental areas.
  • Early Start Denver Model (ESDM): Comprehensive, play-based approach for children 12-48 months. Integrates ABA principles with developmental and relationship-based methods.

  • DIR/Floortime Model: Focuses on emotional development and relationships. Therapists and parents engage with the child based on their interests to promote connection and development.

  • Core Ancillary Therapies:

    • Speech-Language Therapy (SLT): Targets verbal and non-verbal communication.
    • Occupational Therapy (OT): Addresses sensory processing issues and activities of daily living (ADLs).

Exam Favorite: Early and intensive intervention (≥25 hours/week) is the strongest predictor of positive long-term outcomes, more so than the specific therapeutic model chosen.

4 Factors in ABA Therapy Success

High-Yield Points - ⚡ Biggest Takeaways

  • Early diagnosis of ASD, ideally before age 2, is crucial for improving long-term outcomes.
  • Applied Behavior Analysis (ABA) is the most well-established, evidence-based behavioral intervention.
  • Key goals are improving social communication and reducing restrictive/repetitive behaviors.
  • A multidisciplinary team (speech, occupational therapy) is the standard of care.
  • Parental involvement is critical for generalizing skills and improving prognosis.
  • Medications target co-occurring conditions (e.g., ADHD, aggression), not core ASD symptoms.

Practice Questions: Early intervention in ASD

Test your understanding with these related questions

A mother brings her 3-year-old son to the doctor because she is worried that he might be harming himself by constantly banging his head on the wall. He has been exhibiting this behavior for a few months. She is also worried because he has started to speak less than he used to and does not respond when his name is called. He seems aloof during playtime with other children and seems to have lost interest in most of his toys. What is the most likely diagnosis?

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Flashcards: Early intervention in ASD

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Autism spectrum disorder must present in _____ (age group)

TAP TO REVEAL ANSWER

Autism spectrum disorder must present in _____ (age group)

early childhood

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