Cognitive theories of delusion formation

Cognitive theories of delusion formation

Cognitive theories of delusion formation

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Cognitive Models - Brain's Belief Glitches

Two-factor theories of delusion formation

  • Two-Factor Model: Dominant theory. Delusions arise from:

    • Factor 1: An anomalous experience (e.g., strange sensory event, heightened perception).
    • Factor 2: Impaired reasoning that fails to reject the resulting bizarre explanation.
  • Key Cognitive Biases (📌 Mnemonic: J.A.T.):

    • Jumping to Conclusions (JTC): Making firm judgments based on scant evidence.
    • Attributional Style: Externalizing blame for negative outcomes (common in persecutory type).
    • Theory of Mind (ToM) Deficit: Impaired ability to infer others' intentions.

⭐ The "Jumping to Conclusions" (JTC) bias is a classic finding; patients require significantly less data than controls to reach firm, often premature, conclusions.

Explanatory Models - One vs. Two-Factor Theories

  • One-Factor (Bottom-Up) Theory:

    • A single deficit, an anomalous experience (e.g., strange perception), is sufficient to generate a delusion.
    • The delusion is a direct explanation for the experience.
    • Example: Loss of affective response to a face → Capgras belief ("imposter").
  • Two-Factor (Hybrid) Theory:

    • Requires two cognitive deficits.
    • Factor 1 (Bottom-Up): An anomalous experience creates a bizarre hypothesis.
    • Factor 2 (Top-Down): Impaired belief evaluation prevents rejection of the irrational hypothesis.

High-Yield: Two-factor models explain why many with neurological abnormalities (Factor 1) don't develop delusions. Without a second deficit in reality-testing (Factor 2), they can dismiss strange experiences and do not form a fixed, false belief.

Cognitive Biases - The Mind's Usual Suspects

  • Jumping to Conclusions (JTC): Most replicated finding. A tendency to form beliefs with minimal evidence.
    • Assessed via the "beads task" (probabilistic reasoning); patients make a choice with fewer draws.
  • Attributional Biases:
    • Externalizing: Blaming external factors for negative outcomes.
    • Personalizing: Viewing neutral events as self-referential (e.g., "they are laughing at me").
  • Confirmation Bias: Seeking information that confirms one's delusions while ignoring contradictory evidence.
  • Theory of Mind (ToM) Deficits: Impaired ability to infer the mental states of others, leading to misinterpretation of social cues.

⭐ The JTC bias is considered a stable vulnerability marker for psychosis, not just a symptom of active delusions.

Real-Life Paradigm for Jumping to Conclusions Bias

Aberrant Salience Model of Delusion Formation

  • Core Idea: Dysregulated mesolimbic dopamine (DA) causes the brain to assign inappropriate significance ("salience") to neutral thoughts and external stimuli.
  • This is a "bottom-up" neurochemical error.
  • The cortex then creates a "top-down" cognitive narrative (the delusion) to make sense of this aberrant salience.

⭐ Antipsychotics (D2 antagonists) are thought to work by dampening this salience. The delusion may persist, but it feels less important and distressing to the patient.

High-Yield Points - ⚡ Biggest Takeaways

  • Jumping to conclusions (JTC) bias is a core cognitive error, leading to firm beliefs based on minimal evidence.
  • Patients often show externalizing attributional biases, blaming outside forces for negative events.
  • Deficits in Theory of Mind (ToM) impair understanding of others' intentions, fueling persecutory beliefs.
  • Anomalous perceptual experiences can act as the initial seed for a delusional belief system.
  • The two-factor theory requires both an unusual experience and a cognitive bias to explain it.

Practice Questions: Cognitive theories of delusion formation

Test your understanding with these related questions

A 29-year-old woman is brought to the physician by her father because of a change in her behavior over the past 8 months. The father says that his daughter has become increasingly withdrawn; she has not answered any phone calls or visited her family and friends. The patient says that she has to stay at home because a foreign intelligence service is monitoring her. She thinks that they are using a magnetic field to read her mind. Mental status exam shows disjointed and perseverative thinking. She is anxious and has a flat affect. Which of the following is the most likely diagnosis?

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Flashcards: Cognitive theories of delusion formation

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Delusion disorder typically presents with _____ delusions

TAP TO REVEAL ANSWER

Delusion disorder typically presents with _____ delusions

non-bizarre ((bizarre or non-bizarre))

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