Cognitive assessment tools

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Cognitive Screens - Why We Test

  • Establish Baseline: Document cognitive function at a specific point in time for future comparison.
  • Early Detection: Identify mild cognitive impairment (MCI) or early dementia when clinical signs are subtle.
  • Differential Diagnosis: Provide objective data to help distinguish dementia from its mimics.
    • 📌 Key mimics: The 3 D's - Delirium, Depression (pseudodementia), Drugs.
  • Quantify Severity: Objectively score the level of impairment (e.g., mild, moderate, severe).
  • Monitor Progression: Track cognitive changes over time or assess response to any initiated therapy.

⭐ Screening is crucial for uncovering reversible causes of cognitive decline, such as metabolic issues (B12/thyroid), Normal Pressure Hydrocephalus (NPH), or medication side effects.

Differentiating Depression, Dementia, and Delirium

MMSE - The Classic Quiz

  • A 30-point questionnaire for rapid cognitive screening.
  • Scoring:
    • Score <24 suggests cognitive impairment.
    • Adjusted for education level (e.g., add 1 point for <12 years of education).
  • Assesses 5 core areas:
    • Orientation (Time, Place)
    • Registration (Name 3 objects)
    • Attention & Calculation (Serial 7s or spell "WORLD" backward)
    • Recall (Remember the 3 objects)
    • Language & Praxis (Naming, repetition, 3-stage command, writing, copying)
  • Limitations: Insensitive to mild cognitive impairment (MCI) and influenced by education, language, and culture.

⭐ The MMSE is particularly poor at detecting deficits in executive function, making it less sensitive for frontal lobe or subcortical dementias (e.g., frontotemporal dementia, Huntington's).

Mini-Mental State Examination (MMSE) Sample Form

MoCA - The MCI Catcher

  • Name: Montreal Cognitive Assessment (MoCA).
  • Primary Use: Designed to be more sensitive than the MMSE for detecting Mild Cognitive Impairment (MCI).
  • Scoring:
    • Total score: 30 points.
    • Normal score: ≥ 26.
    • Add 1 point for individuals with ≤ 12 years of formal education.
  • Key Domains Assessed:
    • Visuospatial & Executive functions (trail making, cube copy, clock drawing).
    • Naming (animals).
    • Memory (5-word recall).
    • Attention & Concentration.
    • Language (repetition, fluency).
    • Abstraction.
    • Orientation.

Montreal Cognitive Assessment (MoCA) Test Form

⭐ The MoCA's strength lies in its assessment of executive function and attention, domains where deficits may be the first sign of a cognitive disorder, often missed by the MMSE.

Rapid Screens - Mini-Cog & Clock

  • Mini-Cog: A 3-minute screen combining two elements:
    • 3-Word Recall: Score 1 point for each word recalled (0-3).
    • Clock Drawing Test (CDT): Patient draws a clock. Score 2 for normal, 0 for abnormal.
  • Scoring & Interpretation:
    • Total score is out of 5.
    • A score of ≤2 suggests positive for cognitive impairment.

⭐ The Clock Drawing Test is particularly sensitive for executive dysfunction, a core feature of vascular dementia and Lewy body dementia.

  • MMSE: A score <24 suggests cognitive impairment. It is the most widely used tool but is heavily influenced by education and language.
  • MoCA: More sensitive for Mild Cognitive Impairment (MCI) and superior for assessing executive function.
  • Mini-Cog: A rapid screen combining a 3-item recall and the clock-drawing test. It is less biased by language or education.
  • Clock-Drawing Test: Specifically evaluates visuospatial ability and executive function.
  • GDS: The Geriatric Depression Scale is crucial to rule out pseudodementia.

Practice Questions: Cognitive assessment tools

Test your understanding with these related questions

A 72-year-old man is brought to the physician by his wife for memory issues over the last 7 months. The patient's wife feels that he has gradually become more forgetful. He commonly misplaces his car keys and forgets his children's names. He seems to have forgotten how to make dinner and sometimes serves uncooked noodles or raw meat. One night he parked his car in a neighbor's bushes and was found wandering the street. He has a history of hypertension, hyperlipidemia, and COPD. Current medications include atorvastatin, metoprolol, ipratropium, and fluticasone. Vital signs are within normal limits. He is alert and oriented to person and place only. Neurologic examination shows no focal findings. His Mini-Mental State Examination score is 19/30. A complete blood count and serum concentrations of electrolytes, urea nitrogen, creatinine, thyroid-stimulating hormone, liver function tests, vitamin B12 (cobalamin), and folate are within the reference range. Which of the following is the most appropriate next step in diagnosis?

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Flashcards: Cognitive assessment tools

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Vascular dementia is characterized by a step-wise decline in cognitive ability with _____-onset memory impairment

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Vascular dementia is characterized by a step-wise decline in cognitive ability with _____-onset memory impairment

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