Arterial pressure waveform

Arterial pressure waveform

Arterial pressure waveform

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Waveform Morphology - The Heart's Signature

Arterial pressure waveform with labeled components

  • Anacrotic Limb (Systolic Upstroke): Rapid pressure ↑ from ventricular ejection. Its slope reflects myocardial contractility (inotropy).
  • Systolic Peak: The highest pressure point, representing the peak force of left ventricular contraction.
  • Dicrotic Notch: A small dip marking the closure of the aortic valve. It signals the end of systole.
  • Diastolic Runoff: The gradual pressure decline as blood flows to the periphery. The slope is determined by Systemic Vascular Resistance (SVR).

⭐ The dicrotic notch is blunted or disappears in significant aortic regurgitation and in low-pressure states (e.g., septic shock).

Key Pressure Points - Numbers Game

  • Systolic Pressure (SP): Peak pressure during cardiac contraction.
    • Normal: <120 mmHg.
  • Diastolic Pressure (DP): Lowest arterial pressure during cardiac relaxation.
    • Normal: <80 mmHg.
  • Pulse Pressure (PP): The difference between SP and DP; reflects stroke volume.
    • Formula: $PP = SP - DP$
    • Normal: ~40 mmHg.
    • Widened in aortic regurgitation; narrowed in aortic stenosis.
  • Mean Arterial Pressure (MAP): Average pressure driving tissue perfusion.
    • Formula: $MAP \approx DP + \frac{1}{3}(PP)$
    • Must be >60-65 mmHg for adequate organ perfusion.

⭐ The MAP formula weights diastole more heavily because at a normal heart rate, the diastolic phase lasts about twice as long as the systolic phase.

Physiological Factors - What Shapes the Wave

  • Systolic Pressure (SP): Peak pressure during ventricular ejection. Primarily reflects the interplay between stroke volume and aortic compliance.
    • ↑ Stroke Volume (SV) → ↑ SP
    • ↓ Aortic Compliance → ↑ SP
  • Diastolic Pressure (DP): Lowest pressure during ventricular relaxation. Primarily set by systemic vascular resistance (SVR).
    • ↑ SVR → ↑ DP (less peripheral runoff)
    • ↑ Heart Rate → ↑ DP (less diastolic time)
  • Pulse Pressure (PP): The difference, $PP = SP - DP$.
    • Proportional to SV; inversely proportional to compliance.
  • Mean Arterial Pressure (MAP): Average pressure over a cardiac cycle.
    • $MAP \approx DP + \frac{1}{3}PP$

⭐ In arteriosclerosis, decreased aortic compliance is the main driver of isolated systolic hypertension (↑ SP, normal DP), causing a widened pulse pressure. This is a key hemodynamic change in the elderly.

Pathological Waveforms - When Waves Go Wrong

  • Aortic Stenosis: Pulsus parvus et tardus (weak and delayed upstroke). Results in a narrow pulse pressure (↓).
  • Aortic Regurgitation: Pulsus bisferiens (biphasic pulse) and water-hammer pulse. Creates a wide pulse pressure (↑).
  • Hypertrophic Cardiomyopathy (HOCM): Spike-and-dome pattern (bifid pulse) due to LV outflow tract obstruction.

Arterial pressure waveforms: normal and pathological

Pulsus Paradoxus: An exaggerated drop (>10 mmHg) in systolic blood pressure during inspiration. It is a classic sign of cardiac tamponade.

High‑Yield Points - ⚡ Biggest Takeaways

  • The arterial pressure waveform graphically represents pressure changes in an artery throughout the cardiac cycle.
  • The systolic peak corresponds to maximum pressure during left ventricular ejection.
  • The dicrotic notch (incisura) marks the closure of the aortic valve.
  • Pulse pressure (Systolic − Diastolic) is directly proportional to stroke volume.
  • Mean Arterial Pressure (MAP) is approximately Diastolic P + ⅓(Pulse P), critical for ensuring adequate tissue perfusion.
  • A dampened, delayed upstroke (pulsus parvus et tardus) is a classic sign of aortic stenosis.
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Practice Questions: Arterial pressure waveform

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Prior to undergoing a total knee arthroplasty, a 62-year-old man with coronary artery disease undergoes diagnostic cardiac catheterization. The catheter is inserted via the femoral artery and then advanced to the ascending aorta. Pressure tracing of the catheter is shown. The peak marked by the arrow is most likely caused by which of the following?

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Flashcards: Arterial pressure waveform

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What is the effect of aortic regurgitation on systolic pressure? _____

TAP TO REVEAL ANSWER

What is the effect of aortic regurgitation on systolic pressure? _____

Increased pressure

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