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Laboratory findings

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Laboratory findings - The Kawasaki Code

  • Acute phase reactants: Markedly elevated.
      • ↑ ESR (>40 mm/hr)
      • ↑ CRP (>3 mg/dL)
  • Complete Blood Count (CBC):
      • Leukocytosis (>15,000/μL) with neutrophilia.
      • Normocytic, normochromic anemia.
      • Thrombocytosis (platelets >450,000/μL) is a hallmark, peaking in the 2nd-3rd week.
  • Other common findings:
      • ↑ Liver transaminases (ALT).
      • Sterile pyuria.
      • Hypoalbuminemia (<3 g/dL).

⭐ Hyponatremia and hypoalbuminemia are associated with a higher risk of developing coronary artery aneurysms.

High‑Yield Points - ⚡ Biggest Takeaways

  • Thrombocytosis is the most characteristic finding, peaking in the 2nd-3rd week.
  • ↑ ESR & ↑ CRP are universal but non-specific inflammatory markers.
  • Sterile pyuria (WBCs in urine without bacteria) is a classic clue.
  • Aseptic meningitis and ↑ liver enzymes (transaminitis) are common.
  • Normocytic, normochromic anemia is often present.
  • Hyponatremia and hypoalbuminemia can also be seen, indicating severe inflammation.

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