Placental abruption

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Pathophysiology - The Great Separation

  • Primary Event: Rupture of maternal spiral arteries in the decidua basalis.
  • Hematoma Formation: Bleeding leads to a retroplacental hematoma.
    • As the hematoma expands, it shears the placenta off the uterine wall.
    • This separation severely compromises fetal oxygen and nutrient supply.
  • Bleeding Types:
    • Revealed: Blood tracks down and drains through the cervix (visible bleeding).
    • Concealed: Blood is trapped behind the placenta, with no visible external bleeding.

Concealed vs. Revealed Placental Abruption

Disseminated Intravascular Coagulation (DIC) is a major risk. Damaged decidual tissue releases large amounts of tissue factor (thromboplastin) into maternal circulation, triggering the coagulation cascade.

Risk Factors - Recipe for Disaster

  • Prior placental abruption: Strongest predictor, with a 10-15% recurrence risk.
  • Maternal hypertensive disorders:
    • Chronic hypertension
    • Preeclampsia / eclampsia
  • Trauma:
    • Blunt abdominal trauma (e.g., MVA, falls, domestic violence)
  • Substance use:
    • Cocaine (vasoconstriction)
    • Tobacco smoking
  • Sudden uterine decompression:
    • Amniorrhexis with polyhydramnios
    • Delivery of the first twin
  • Other key factors:
    • PPROM (Prelabor Rupture of Membranes)
    • Advanced maternal age (AMA)
    • Thrombophilias

⭐ A history of abruption in a previous pregnancy is the single most important risk factor.

Clinical Presentation - Code Red

  • Sudden-onset, severe abdominal pain or backache.
  • Painful, dark vaginal bleeding (⚠️ can be concealed in 20% of cases).
  • Uterine findings:
    • Tender, firm-to-rigid consistency.
    • High-frequency, low-amplitude contractions (tetanic).
  • Maternal instability:
    • Tachycardia, hypotension (signs of shock).
    • Risk of Disseminated Intravascular Coagulopathy (DIC).
  • Fetal distress:
    • Non-reassuring fetal heart rate patterns (bradycardia, late decelerations).
    • Sinusoidal pattern is an ominous sign.

High-Yield: The amount of visible vaginal bleeding does not correlate with the degree of maternal hemorrhage, as a significant volume can be trapped behind the placenta (concealed abruption).

Diagnosis & Management - Damage Control

  • Maternal Stabilization First: Priority is aggressive resuscitation.
    • Secure airway; administer supplemental O₂.
    • Place 2 large-bore IVs (≥16-gauge).
    • Begin rapid infusion of crystalloids.
    • Transfuse blood products (PRBCs, FFP, platelets) for hemorrhage & coagulopathy.

Placental Abruption with Retroplacental Hematoma

  • Delivery Decision Algorithm:

⭐ Be prepared for Disseminated Intravascular Coagulation (DIC). The large retroplacental hematoma releases tissue factor (thromboplastin), triggering a massive consumptive coagulopathy.

High‑Yield Points - ⚡ Biggest Takeaways

  • Painful third-trimester vaginal bleeding is the hallmark sign, unlike the painless bleeding of placenta previa.
  • Strongly associated with maternal hypertension, cocaine use, and abdominal trauma.
  • Diagnosis is clinical; ultrasound may show a retroplacental hematoma but is not sensitive.
  • Risk of Disseminated Intravascular Coagulation (DIC) from thromboplastin release.
  • Can present with a tender, rigid (hypertonic) uterus.
  • Management requires immediate C-section for fetal or maternal distress.

Practice Questions: Placental abruption

Test your understanding with these related questions

A 26-year-old Caucasian G1 presents at 35 weeks gestation with mild vaginal bleeding. She reports no abdominal pain or uterine contractions. She received no prenatal care after 20 weeks gestation because she was traveling. Prior to the current pregnancy, she used oral contraception. At 22 years of age she underwent a cervical polypectomy. She has a 5 pack-year smoking history. The blood pressure is 115/70 mmHg, the heart rate is 88/min, the respiratory rate is 14/min, and the temperature is 36.7℃ (98℉). Abdominal palpation reveals no uterine tenderness or contractions. The fundus is palpable between the umbilicus and the xiphoid process. An ultrasound exam shows placental extension over the internal cervical os. Which of the following factors present in this patient is the risk factor for her condition?

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Flashcards: Placental abruption

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Disseminated intravascular coagulation may occur secondary to obstetric complications due to activation of the coagulation cascade by _____ in the amniotic fluid

TAP TO REVEAL ANSWER

Disseminated intravascular coagulation may occur secondary to obstetric complications due to activation of the coagulation cascade by _____ in the amniotic fluid

tissue thromboplastin

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