Conflict of interest management

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Conflicts of Interest - Money & Medicine

  • Definition: Arises when a primary interest (e.g., patient welfare, research integrity) is potentially influenced by a secondary interest (e.g., financial gain).
  • Common Sources:
    • Industry-sponsored meals, gifts, travel
    • Speaking & consulting fees (honoraria)
    • Research grants
    • Stock or equity interests
  • Management: The primary ethical duty is transparency. Full disclosure to employers, IRBs, and patients is essential. May require recusal.

⭐ The Physician Payments Sunshine Act (Open Payments Program) requires manufacturers to report payments and transfers of value to physicians and teaching hospitals.

Open Payments: Reporting Entities to Covered Recipients

COI Flavors - More Than Just Cash

Conflicts of interest (COI) extend beyond direct financial gain, creating subtle biases that can compromise professional judgment in patient care, research, and education. Awareness of these non-financial influences is critical for maintaining trust and objectivity.

  • Personal & Family Relationships: Bias from loyalty to friends, family, or close colleagues, potentially affecting referrals, hiring, or peer review.
  • Professional Advancement: Desire for promotion, tenure, or prestigious appointments may influence research conduct or reporting.
  • Intellectual COI: A researcher's strong commitment to their own theory can impair objectivity when evaluating competing ideas.
  • Gifts & Perks (In-kind COI): Includes sponsored travel, meals, or entertainment. Even small gifts can create a sense of reciprocity.

⭐ The Physician Payments Sunshine Act requires public reporting of financial ties and transfers of value over $10 between manufacturers (drug/device) and physicians/teaching hospitals.

Conflict of Interest in Academia

Taming the Beast - Handling COIs

  • Core Principle: Transparency. The primary step in managing any potential conflict of interest is full disclosure to all relevant parties (institution, IRB, patients).
  • Goal: To safeguard patient welfare and maintain the integrity of research and clinical judgment.

⭐ The Physician Payments Sunshine Act requires public reporting of financial relationships between drug/device manufacturers and physicians/teaching hospitals. This data is publicly available on the CMS "Open Payments" website.

High‑Yield Points - ⚡ Biggest Takeaways

  • A conflict of interest arises when a primary interest (e.g., patient welfare) is potentially influenced by a secondary interest (e.g., financial gain).
  • The primary goal is management and mitigation, not necessarily total elimination of the secondary interest.
  • Full disclosure to patients, institutions, and journals is the most critical step in management.
  • Even the perception of a conflict can erode patient trust as much as an actual conflict.
  • Institutional Review Boards (IRBs) and specific committees oversee and manage these conflicts.

Practice Questions: Conflict of interest management

Test your understanding with these related questions

A 76-year-old man is brought to the hospital after having a stroke. Head CT is done in the emergency department and shows intracranial hemorrhage. Upon arrival to the ED he is verbally non-responsive and withdraws only to pain. He does not open his eyes. He is transferred to the medical ICU for further management and intubated for airway protection. During his second day in the ICU, his blood pressure is measured as 91/54 mmHg and pulse is 120/min. He is given fluids and antibiotics, but he progresses to renal failure and his mental status deteriorates. The physicians in the ICU ask the patient’s family what his wishes are for end-of-life care. His wife tells the team that she is durable power of attorney for the patient and provides appropriate documentation. She mentions that he did not have a living will, but she believes that he would want care withdrawn in this situation, and therefore asks the team to withdraw care at this point. The patient’s daughter vehemently disagrees and believes it is in the best interest of her father, the patient, to continue all care. Based on this information, what is the best course of action for the physician team?

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Flashcards: Conflict of interest management

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Which ego defense is defined as demonstrating hostile feelings in a non-confrontational manner?_____

TAP TO REVEAL ANSWER

Which ego defense is defined as demonstrating hostile feelings in a non-confrontational manner?_____

Passive aggression (immature defense)

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