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Pain Assessment and Management

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Understanding Pain - The Palliative Puzzle

  • Pain: Unpleasant sensory & emotional experience linked to actual/potential tissue damage (WHO).
  • Total Pain (Cicely Saunders): Physical, psychological, social, spiritual dimensions. Holistic approach vital.
  • Types & Characteristics:
    • Nociceptive:
      • Somatic: Localized, aching, throbbing (e.g., bone mets).
      • Visceral: Diffuse, cramping, gnawing (e.g., organ distension).
    • Neuropathic: Nerve injury; burning, shooting, tingling, "pins & needles".
  • Assessment: Self-report is gold standard 💡. Use scales (NRS, VAS, Faces Pain Scale).

⭐ "Total Pain" (Saunders): physical, psychological, social, spiritual dimensions; crucial for holistic palliative care.

Assessing Agony - Detective Work

  • Core Principle: Pain is subjective; patient's report is key.
  • Systematic Assessment:
    • History: Patient's words. 📌 SOCRATES: Site, Onset, Character, Radiation, Assoc. symptoms, Timing, Exacerb/Relief, Severity.
    • Impact: On daily activities, sleep, mood.
    • Physical Exam: Source, tenderness, neuro signs.
  • Pain Scales:
    • NRS (Numeric Rating Scale): 0-10.
    • VAS (Visual Analog Scale): 100mm line.
    • Wong-Baker FACES: Children ≥3 yrs, cognitive/verbal impair.
    • VDS (Verbal Descriptor Scale): Mild, moderate, severe.
    • BPS/CPOT (Behavioral Pain Scale/Critical-Care Pain Observation Tool): Non-verbal/ICU. Pain Assessment Scales

⭐ Wong-Baker FACES Scale: validated for children ≥3 yrs; preferred if unable to use numeric scales.

The Analgesic Arsenal - Step by Step

  • WHO Ladder Principles: 📌 By Mouth, By Clock, By Ladder, Individualized Dosing.
  • Non-Opioids (Step 1):
    • Paracetamol: Max 4g/day (adults).
    • NSAIDs (e.g., Ibuprofen, Diclofenac): GI & renal risk. COX-2 inhibitors (Etoricoxib) safer for GI.
  • Weak Opioids (Step 2):
    • Tramadol: 50-100mg q4-6h (max 400mg/day). Seizure risk.
    • Codeine: Often with paracetamol. Constipation.
  • Strong Opioids (Step 3):
    • Morphine (oral): Start 5-10mg q4h for opioid-naive.
    • Fentanyl (patch): For stable, chronic pain. Not for acute pain or opioid-naive.
  • Adjuvant Analgesics (All Steps):
    • Neuropathic pain: Gabapentin, Pregabalin, Amitriptyline.
    • Bone pain: Corticosteroids (Dexamethasone), Bisphosphonates.

⭐ Morphine is the gold standard and first-line strong opioid for moderate to severe cancer pain management according to WHO guidelines; initiate with immediate-release oral morphine.

Opioid Power - Taming the Beast

  • Principle: WHO Ladder Step 2 (weak) & 3 (strong) for moderate-severe pain.
    • Weak: Tramadol, Codeine.
    • Strong: Morphine (Gold Standard), Fentanyl, Methadone, Oxycodone.
  • Titration: "Start Low, Go Slow".
    • Breakthrough Pain (BTP): Rescue dose 10-15% of 24-hr total, q1-4h PRN.
  • Opioid Rotation: For poor efficacy or intolerable side effects.
    • Use equianalgesic doses; reduce new opioid by 25-50% (incomplete cross-tolerance).
  • Key Side Effects & Management:
    • Constipation: Universal. Prophylactic laxatives (stimulant + softener).
    • Nausea/Vomiting: Common. Antiemetics (Metoclopramide).
    • Sedation: Usually transient.
    • Respiratory Depression: Rare. Antidote: Naloxone (0.4mg IV/IM).
    • 📌 Mnemonic (Common): Constipation, Nausea, Sedation (CNS). WHO three-step analgesic ladder for pain management
  • Important Notes:
    • Fentanyl patch: For stable pain, not opioid-naïve. Change q72h.
    • Methadone: Long half-life, good for neuropathic pain. Careful initiation.

⭐ Oral morphine is the first-line strong opioid for cancer pain management as per WHO guidelines, valued for its efficacy and multiple administration routes.

High‑Yield Points - ⚡ Biggest Takeaways

  • Pain assessment is key; use scales like NRS or VAS.
  • The WHO analgesic ladder guides stepwise management, starting with non-opioids.
  • Morphine is the gold standard strong opioid; titrate dose carefully.
  • Proactively manage opioid side effects: constipation (laxatives), nausea (antiemetics).
  • Use adjuvant analgesics like gabapentin for neuropathic pain or NSAIDs.
  • Address breakthrough pain with short-acting opioids.
  • Recognize total pain: physical, psychological, social, spiritual aspects_._

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